3724 papers
This study demonstrates that while the ER chaperone BiP is dispensable for maintaining pluripotency in human embryonic stem cells, it is essential for coordinating the unfolded protein response with mitochondrial respiration to ensure stress resilience and prevent dissociation-induced apoptosis.
This study presents the complete mitochondrial genome of a *Naemorhedus goral* from Wanglang National Nature Reserve, detailing its structural features, codon usage patterns, and evolutionary characteristics of protein-coding genes to provide an independently archived sequence for comparative analysis within the Caprinae subfamily.
This study validates the SSM6 marker as a reliable, female-specific DNA tool for early molecular sex determination in Beluga and Ship sturgeons, demonstrating its evolutionary conservation across ploidy levels and its potential to improve broodstock management and aquaculture practices.
Moderate drought triggers tuberous root formation in *Potentilla anserina* by downregulating the PaCCR1-mediated lignin biosynthesis pathway, thereby redirecting carbon flux from structural lignin production to soluble sugar and starch accumulation to facilitate radial root expansion.
This study utilizes whole-genome resequencing of 49 Saudi Arabian pearl millet accessions to characterize their population structure and genetic diversity, ultimately developing a highly discriminating 150-SNP fingerprinting panel integrated with QR-code technology for effective digital germplasm management.
This study utilizes whole-transcriptome sequencing of peripheral blood to characterize progressive dysregulation of mRNAs, lncRNAs, circRNAs, and miRNAs across health, sepsis, and sepsis-associated ARDS, revealing a remodeled ceRNA network that drives immune-inflammatory activation, extracellular matrix remodeling, and barrier dysfunction.
This systematic review and meta-analysis reveals that while polygenic risk scores for breast cancer show modest predictive performance in African populations, European-derived models currently outperform those developed specifically for African ancestry, underscoring the critical need for greater genomic representation and recalibration to improve clinical utility.
This review of 100 studies examines the interdisciplinary convergence of Artificial Intelligence and Cognitive Neuroscience, highlighting memory and attention as dominant research domains while addressing key technological applications, emerging directions like explainable AI, and critical ethical challenges to advocate for sustained collaboration in developing biologically grounded and socially responsible intelligent systems.
This study demonstrates that increasing cognitive dual-task complexity significantly alters phase-specific gait performance and stability in healthy middle-aged adults, particularly during the walking-back phase, highlighting the value of instrumented Timed Up and Go analysis for detecting early cognitive-motor interference.
This study reveals that the endemic Noronha Vireo exhibits unusually high nest survival compared to the more vulnerable Noronha Elaenia, whose lower success rates highlight the urgent need for conservation measures such as invasive predator removal and habitat restoration on Fernando de Noronha.