5759 papers
This study reveals that aging-induced inflammation in paraventricular hypothalamic neurons disrupts the brain–bone marrow axis to impair lymphopoiesis, and demonstrates that chemogenetically inhibiting these neurons or ablating their TLR4 receptors can rejuvenate immune function and improve vaccine responses in aged mice.
This study reveals that koalas in peri-urban areas exhibit lower disease prevalence and different stress hormone profiles compared to those in rural or national park settings, suggesting that suitable human-modified habitats may support coexistence despite threats like KoRV and Chlamydia, although no direct correlation was found between stress hormones and disease measures.
This field study utilizing wearable EEG and a PCA Transformer model reveals that mental fatigue follows a nonlinear accumulation process characterized by shifting brain network dynamics, suggesting that safety management should prioritize monitoring risk fluctuations across work periods rather than relying solely on cumulative work duration.
This paper investigates localized aggregation patterns in a diffusive population-toxicant model with negative toxicant-taxis, demonstrating that while boundary spikes are stable, interior spikes are unstable and drift toward domain boundaries or stable toxicant minima depending on environmental homogeneity.
This paper evaluates a Quantum Bayesian Machine (QBM) for predicting relaxed energies of metal-oxide catalysts, finding that while specific quantum-enhanced configurations yield marginal in-distribution accuracy gains over classical baselines, they fail to demonstrate out-of-distribution improvements and are limited by incomplete data provenance and idealized simulation constraints.
This paper introduces a hippocampal-inspired dynamic gating model demonstrating how selective memory operations, such as encoding disruptions and output-gain modulation, shape history-dependent population representations and behavioral choices under sensory ambiguity.
Cell IO is a freely accessible database that integrates re-processed single-cell transcriptome data from nearly 15,000 experiments with over 895,000 literature-derived claims about cell functions and perturbations, linking them through Cell Ontology identifiers to enable comprehensive exploration of cell type biology.
This study demonstrates that cross-regime comparisons of postprandial glucose prediction models are fundamentally confounded by measurement reliability, revealing that reported performance gaps often reflect differences in data quality and regimes rather than true model superiority, and urging the field to standardize reporting by explicitly naming measurement regimes and including reliability estimates.
This study characterizes the spatiotemporal boundaries of functional ultrasound (fUS) signals in awake mice by systematically varying whisker stimulation parameters, demonstrating that fUS-CBV signals retain structured spatial and temporal information suitable for reliable brain decoding and providing essential constraints for future fUS-based modeling and experimental design.
This paper establishes that for finite-sample microchannel biosensors, the optimal flow rate equals the sample volume divided by the assay time, and derives universal, closed-form design rules based on two dimensionless groups that accurately predict capture efficiency while demonstrating that excessive flow rates significantly degrade detection limits.