🧬 biology

Genetic differentiation and pathogenicity of diverse Xanthomonas oryzae pv. oryzae strains revealed by Whole Genome Sequencing

This study utilizes whole-genome sequencing of ten diverse *Xanthomonas oryzae* pv. *oryzae* strains to demonstrate that while core virulence and resistance genes are highly conserved, the extensive diversification of TAL effector repertoires drives genomic differentiation and host adaptation within the pathogen population.

Shanyu Chen, Yun Zhang, Jiaxin Xing, Li Liu, Tengqiong Yu, Fuyou Yin, Qiaofang Zhong, Jinlu Li, Dunyu Zhang, Suqin Xiao (…)2026-09-07
🧬 biology

Development of a Biomimetic Agarose–Calcium Lactate Gluconate Composite Scaffold for Trabecular Bone Regeneration

This study demonstrates that freeze-dried agarose scaffolds functionalized with calcium lactate gluconate (CLG) possess enhanced mechanical properties, biocompatibility, and osteogenic potential, making them a promising candidate for trabecular bone regeneration.

Shanmathy Somasundaram, Rajan Choudary, Elango Natarajan, Suresh Kumar Anandasadagopan, Gayathri Veeraraghavan, Balaji R (…)2026-09-07
🧬 biology

Range extension of Habenaria gibsonii var. foetida to the northwestern Himalaya of India

This paper reports the first discovery of the terrestrial orchid *Habenaria gibsonii* var. *foetida* in the North-Western Himalaya of India, specifically in the Shivalik Hills of Uttarakhand, where a single flowering individual was documented to extend the species' known range and underscore the need for continued conservation-focused botanical exploration.

Revan Yogesh Chaudhari, Monal Rajendra Jadhav, Saurabh Anil Mahajan, Tanveer A Khan2026-09-07
🧬 biology

Cell-type-specific QKI signaling drives stromal-epithelial oncogenesis in pancreatic cancer through distinct YAP phosphorylation mechanisms

This study reveals that cell-type-specific QKI signaling drives pancreatic cancer oncogenesis by distinctively promoting YAP Y357 phosphorylation in cancer-associated fibroblasts via TNC interaction while suppressing YAP S127 phosphorylation in cancer cells through α-catenin downregulation, thereby orchestrating a critical stromal-epithelial dialogue.

Guo Chen, Yonqquan Bai, Dongsheng Zhai, Wenli Zhang, Zifan Lu2026-09-07
🧬 biology

Spatial Proteomics and Epigenomics Reveal Cell Morphology and Epigenetic Gene Regulation in Human Hippocampus

This study presents the first comprehensive spatial tri-omic atlas of the human hippocampus, integrating single-cell proteomics, transcriptomics, and epigenomics to map cell morphology, gene regulation, and subfield-specific chromatin landscapes across over 1.6 million cells from 16 individuals.

Rong Fan, Yang Xiao, Graham Su, Yuqi Tan, Nima Assad, Yanxiang Deng, Tianyu Li, Yao Lu, Dongjoo Kim, Gorazd Rosoklija, A (…)2026-09-07
🧬 biology

Beyond 30%: strategic strict protection delivers disproportionate biodiversity gains

This study demonstrates that in the Netherlands, strategically allocating 10% of land to strict protection yields disproportionately greater biodiversity gains and reduces threatened species deficits far more effectively than simply expanding the existing protected area network to 30% coverage, highlighting that conservation success depends on strategic configuration and protection intensity rather than mere area expansion.

Kaixuan Pan, Jacobus C. Biesmeijer, Dylan Verheul, Niels Raes, Leon Marshall2026-09-07