1504 papers
This longitudinal multi-omics study of 294 mother-infant dyads in rural Burkina Faso reveals that growth faltering in small vulnerable newborns is driven by prenatal maternal vulnerabilities and postnatal disruptions in milk composition and infant gut ecology, with specific milk amino acids partially mediating persistent linear growth deficits.
This study reveals that pathogenic fungi in drinking water systems significantly enhance their chlorine resistance by actively binding metal ions from pipe corrosion, which triggers a multilayered defense mechanism involving physical barriers, chemical consumption, and intracellular metabolic remodeling that collectively impedes disinfection efficacy.
This randomized controlled study demonstrates that comparative feedback, particularly better-than-average feedback, significantly enhances motor performance, psychological states, and neurophysiological regulation in low-skilled golfers undergoing single-session EEG neurofeedback training compared to worse-than-average or control conditions.
This paper proposes the CEDAR hypothesis, which posits that centrioles act as physical barriers to cellular reprogramming via a "Centrosome-Associated Memory Complex" (CAMC), and outlines a feasible three-year experimental framework to test whether eliminating centrioles from somatic cells prior to Yamanaka factor exposure enhances reprogramming efficiency by removing this epigenetic lock.
This study analyzes 19 Ugandan Bundibugyo Ebolavirus (BDBV-2026) genomes to characterize novel mutations, evolutionary dynamics, and protein stabilizing effects, suggesting a recent zoonotic spillover origin and providing critical insights for vaccine and therapeutic design.
This study investigates high-frequency T-DNA truncation in "Princettia" poinsettia transformants and proposes a novel model where long inverted repeat sequences flanking breakpoints trigger truncation and the addition of extra DNA sequences.
This study presents a systematic comparative-genomic survey of 1,024 archaeal genomes that quantifies the coding potential for stress-survival effectors and sequence-specific DNA-binding regulators, revealing a near-universal stress toolkit and a lineage-dependent, super-linearly scaling regulatory architecture that serves as a structural analogue to eukaryotic REST/NRSF logic, while explicitly noting that these findings represent genetic potential rather than confirmed physiological behavior.
This study identifies that RNA secondary structures folding below the nanopore during direct RNA sequencing cause systematic ionic current distortions and false-positive modification calls, thereby establishing a critical need for structure-aware models to improve sequencing fidelity.
This study demonstrates that the ingestion of polyethylene terephthalate (PET) nanoplastics, commonly found in water bottles, induces severe long-term gut inflammation, microbiome dysbiosis, and genotoxicity in mice, posing greater risks to gastrointestinal health than polystyrene nanoplastics.
By analyzing three large-scale developmental cohorts, this study reveals that the human hippocampus is organized into three reproducible gradients with distinct maturational trajectories that progressively relax geometric constraints to orchestrate cortical hierarchy and support the development of episodic memory and executive functions.