🧬 biology

Seismic activity temporarily reshapes fin whale foraging radii

Using a deep learning-based acoustic localization model, this study demonstrates that submarine seismic events in the southwestern Indian Ocean cause significant, transient contractions in fin whale foraging radii, revealing a direct tectonic–biological linkage where acoustic disturbances force spatial restrictions that may lead to localized prey depletion.

Xuefeng Zhang, Xiaozhao Zhou, Jian Xu, Wen Zhang, Jun Wang, Ruixue Xia, Yuan Niu2026-09-07
🧬 biology

Characterization of N-Glycosylation Remodeling in Cerebrospinal Fluid Extracellular Vesicles in Children with Purulent Meningitis and Viral Meningitis: An Exploratory Glycomics Study Based on MALDI-TOF/TOF-MS

This exploratory study demonstrates that cerebrospinal fluid extracellular vesicles in children with purulent and viral meningitis exhibit distinct N-glycosylation remodeling patterns compared to disease controls, characterized by specific alterations in sialylation, galactosylation, and core fucosylation that correlate with inflammatory markers.

YUJIA RUAN, Yinfeng Shen2026-09-07
🧬 biology

Synergy of PMBN and closantel against mcr-1-carrying multidrug- resistant E. coli and Salmonella via membrane permeabilization- driven accumulation and metabolic disruption

This study demonstrates that combining polymyxin B nonapeptide (PMBN) with closantel restores potent bactericidal activity against mcr-1-carrying multidrug-resistant *E. coli* and *Salmonella* by permeabilizing the outer membrane to drive intracellular drug accumulation, leading to ATP depletion, metabolic collapse, and effective in vivo therapeutic outcomes.

Wenying Guo, Zhimin Sun, Qiuhong Liu, Jingqi Wang, Wenjuan Meng, Meiling Zhu, Limin He, Yafei Li, Liangxing Fang2026-09-07
🧬 biology

Protein expression of short-chain dehydrogenases/reductases and their inducibility by flubendazole in Haemonchus contortus

This study presents the first targeted proteomic characterization of short-chain dehydrogenases/reductases (SDRs) in *Haemonchus contortus*, revealing sex-dependent expression patterns and identifying specific SDR isozymes that exhibit both constitutive overexpression in benzimidazole-resistant strains and inducibility by flubendazole, suggesting their potential role in anthelmintic adaptation.

Michaela Šadibolová, Karolína Štěrbová, Nikola Slaninová, Nicole Lübbehusen, Thomas Ruppert, Marcin Luzarowski, Petra Ma (…)2026-09-07
🧬 biology

Antimicrobial Activity and Integrated In Silico Evaluation of Bioactive Constituents from Trametes versicolor against Clinically Isolated Pathogens

This study demonstrates that sawdust supplementation significantly enhances the yield of *Trametes versicolor*, whose methanol extract exhibits potent antimicrobial activity against clinically isolated pathogens, with integrated in silico analyses identifying specific bioactive constituents as promising leads for targeting bacterial DNA gyrase B.

Fanna Abba Ali Garra, Mustafa Alhaji Isa, Adam Mustapha, Abubakar Shettima, Ahmed Abba Tor2026-09-07
🧬 biology

Discovery and Characterization of Novel Fluorescent Proteins and Chromoproteins from the Intertidal Sea Anemone Anthopleura dowii Verrill 1869

This study identifies and characterizes three novel fluorescent and chromoprotein variants from the sea anemone *Anthopleura dowii*, demonstrating their temperature-dependent solubility in *E. coli* and highlighting their potential as biotechnological tools while offering an explanation for the organism's color polymorphism.

Paul Gaytán, Paola Linares-Flores, Abigail Roldán-Salgado, Edith Bernabé-Pérez, Jorge Arturo Yáñez, Gloria Saab-Rincón (…)2026-09-07