3821 papers
This study demonstrates that the standard genetic code's superior error-minimization capability arises not merely from specific amino acid assignments but from an intrinsic optimization threshold enabled by triplet architecture, which leverages wobble-position synonymy to absorb translation errors far more effectively than doublet codes.
This study integrates GWAS, gene expression, haplotype, and evolutionary genomic analyses to delineate the genetic architecture of salt tolerance in maize seedlings, identifying four high-confidence candidate genes and elite haplotypes that offer valuable resources for breeding salt-resilient cultivars.
This study utilizes transcriptomic analysis to reveal that the biocontrol bacterium *Bacillus licheniformis* M2-7 exerts its antagonistic effect against the maize pathogen *Curvularia lunata* by upregulating sporulation-related genes, leading to fungal hyphal deformation and reduced germination.
This study identifies microglial Programmed Cell Death 5 (PDCD5) as a novel pro-inflammatory regulator in ischemic stroke that directly binds to IKKβ to activate NF-κB and NLRP3 signaling, thereby driving neuroinflammation and suggesting it as a promising therapeutic target.
This study demonstrates that biodegradable, electroconductive scaffolds fabricated from thermoplastic polyurethane, chitosan, and polypyrrole exhibit optimized physicochemical, mechanical, and biological properties that effectively support cell adhesion, growth, and angiogenesis for cardiac tissue engineering applications.
Licochalcone B ameliorates DSS-induced ulcerative colitis in mice by inhibiting the PI3K/AKT signaling pathway, restoring purine metabolism, and reinforcing intestinal barrier integrity.
This study presents the assembly and comparative analysis of mitogenomes from *Perilla frutescens* and four closely related taxa using whole-genome sequencing data, revealing conserved gene content and low evolutionary divergence alongside significant structural variations in repeats, collinearity, and plastid DNA insertions.
This study demonstrates that met-enkephalin, released from the amygdalo-striatal transition zone via volume transmission to the lateral amygdala, dynamically constrains fear learning by suppressing dopamine release through µ-opioid receptors.
This study leverages citizen science data to reveal that 17 non-native palm taxa are already naturalizing in South Africa, far exceeding current official records, and uses this information to model habitat suitability and identify high-priority urban areas for early detection and management.
This study identifies a gibberellin-responsive AcMYB108 signaling cascade that activates WRKY transcription factors to induce senescence-associated protease expression, thereby elucidating the molecular mechanism behind internal browning in pineapple and offering strategies to mitigate postharvest losses.