3821 papers
This study of 735 young adults reveals that sleep dysfunction bidirectionally mediates the relationship between reduced hemodynamic response height in the secondary somatosensory cortex and increased fear-somatic symptom severity.
This paper develops a reproducible numerical framework that couples a five-compartment Caputo fractional-order schistosomiasis model with a two-hidden-layer radial basis function neural network to create a highly accurate and computationally efficient surrogate for reference trajectories generated by the Adams–Bashforth–Moulton method.
This case-control study of pulmonary tuberculosis patients in Punjab, Pakistan, identifies the TNF-308 G/A polymorphism and specific TNF and IL10 haplotypes as significant genetic modulators influencing TB susceptibility and disease risk.
This study reveals that mild traumatic brain injury patients with cognitive impairment exhibit distinct gut microbiota alterations and disrupted anterior insular functional connectivity, suggesting a potential gut-brain axis mechanism involving specific bacterial genera that may contribute to mood disorders and cognitive deficits.
This study demonstrates that the Dreem3 wearable EEG headband successfully replicates established age-related trends in sleep macro- and micro-architecture across adolescence, validating it as an accessible alternative to traditional laboratory polysomnography for characterizing sleep physiology development.
This study demonstrates that acute, reversible optogenetic perturbation of proprioceptive inputs in mice impairs memory-dependent spatial navigation, providing the first causal evidence for the peripheral nervous system's role in path-integration biomechanics.
This study integrates bulk and single-cell RNA sequencing with experimental validation to identify ACOT12 and SLC16A1 as pivotal pyruvate metabolism-related genes in nonalcoholic fatty liver disease, elucidating their roles in immune infiltration and disease progression while proposing potential therapeutic small molecules.
This study reveals that living cells on soft elastomer substrates primarily respond to the material's substantial interface tension rather than its Young's modulus, a finding that explains discrepancies between elastomer and hydrogel studies and enables a new physical model for predicting cellular mechanosensing behavior.
This study demonstrates that sports experience, specifically in basketball and table tennis, facilitates earlier pro-saccade reaction times under a gap task when maintaining a neck flexion position, with the specific distributional changes varying by sport type compared to non-athletic controls.
This study identifies RGS10 as a critical, sex-dependent upstream regulator of the NLRP3 inflammasome in male mice, demonstrating that its loss abolishes the metabolic and neuroinflammatory benefits of NLRP3 suppression in diet-induced obesity and suggesting that age-related RGS10 decline may limit the efficacy of NLRP3-targeted therapies.