Prolactin Modulates Renal Ischemia Reperfusion Injury According to Sex and Cathepsin D Genotype
This study demonstrates that the Cathepsin D-prolactin axis differentially regulates renal ischemia-reperfusion injury outcomes in a sex-specific manner, where Cathepsin D heterozygosity and prolactin levels modulate inflammatory and angiogenic responses to either protect against or exacerbate kidney damage.
Original paper dedicated to the public domain under CC0 1.0 (https://creativecommons.org/publicdomain/zero/1.0/). This is an AI-generated explanation of a preprint that has not been peer-reviewed. It is not medical advice. Do not make health decisions based on this content. Read full disclaimer
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