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Free-to-total PSA Ratio Predicts PSMA PET Uptake in Treatment-naive Prostate Cancer

This study demonstrates that a free-to-total PSA ratio cut-off of 0.09 serves as a highly effective non-invasive predictor for PSMA PET positivity in treatment-naïve prostate cancer, achieving a 100% negative predictive value that could enable the safe deferral of PSMA PET scans in patients with low ratios, particularly those with PI-RADS 3 lesions.

Original authors: zheng zhang, Jiale Liu, Xiaomeng Li, Xiaoyan Wu, Jiayi Xiong, Yongquan Hu, Yifan Zhang, Yu Li, Hong Sun

Published 2026-10-14
📖 1 min read☕ Coffee break read

Original authors: zheng zhang, Jiale Liu, Xiaomeng Li, Xiaoyan Wu, Jiayi Xiong, Yongquan Hu, Yifan Zhang, Yu Li, Hong Sun

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

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