A genomically validated loss of chromosome Y transcriptional program is a modest prognostic signal independent of tumour stage in male lung adenocarcinoma
In male lung adenocarcinoma, a genomically validated loss of chromosome Y (LOY) transcriptional program serves as a modest, statistically significant prognostic signal that is only marginally independent of tumor stage and is largely confounded by generic proliferation, limiting its immediate utility as a standalone clinical biomarker.
Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of a preprint that has not been peer-reviewed. It is not medical advice. Do not make health decisions based on this content. Read full disclaimer
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