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Plasma exosomal miR-29b promotes the progression of endometrial cancer by activating the Wnt/β-catenin signaling pathway via FOLR1-mediated regulation of CTNNB1

This study demonstrates that reduced plasma exosomal miR-29b promotes endometrial cancer progression by upregulating FOLR1, which stabilizes CTNNB1 to activate the Wnt/β-catenin signaling pathway, thereby identifying a novel molecular axis for potential biomarkers and therapeutic targets.

Original authors: Jinqiu Su, Jiayuan Du, Yaojie Yu, Mei Feng, Qiuyue Huang, Bing Liu, He Wang

Published 2026-10-11
📖 1 min read☕ Coffee break read

Original authors: Jinqiu Su, Jiayuan Du, Yaojie Yu, Mei Feng, Qiuyue Huang, Bing Liu, He Wang

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ⚕️ This is an AI-generated explanation of a preprint that has not been peer-reviewed. It is not medical advice. Do not make health decisions based on this content. Read full disclaimer

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