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Sacubitril/Valsartan Versus Valsartan in Elderly Patients With Acute Myocardial Infarction and Hypertension: Effects on Ventricular Remodeling and Short-term Prognosis After PCI: A Prospective Randomized Controlled Study

This prospective randomized controlled trial demonstrates that early initiation of sacubitril/valsartan, compared to valsartan, in elderly patients with acute myocardial infarction and hypertension following PCI significantly improves cardiac function, attenuates ventricular remodeling and inflammation, and reduces short-term major adverse cardiovascular events without increasing hypotension risk.

Original authors: Yong WANG, Zichang LIU, Xuesheng XU, Wenkun GE

Published 2026-08-31
📖 1 min read☕ Coffee break read

Original authors: Yong WANG, Zichang LIU, Xuesheng XU, Wenkun GE

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

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