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Suxiao Jiuxin Pills Attenuate Myocardial Ischemia Injury through Multi-Component Synergy and Ligustilide-Mediated AKT/GSK3β/HIF-1α Pathway Activation

This study demonstrates that Suxiao Jiuxin Pills protect against myocardial ischemia injury by improving cardiac function and reducing infarction, a therapeutic effect largely driven by the compound ligustilide activating the AKT/GSK3β pathway to suppress HIF-1α overexpression and stabilize mitochondrial homeostasis.

Original authors: yue weng, Xinyu he, Peishuang yu, Yujie gong, Xueke liu, Yanyan xu, shenshen yang

Published 2026-09-29
📖 1 min read☕ Coffee break read

Original authors: yue weng, Xinyu he, Peishuang yu, Yujie gong, Xueke liu, Yanyan xu, shenshen yang

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

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