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Surgical management of Empty Nose Syndrome Using Inferior Meatus Volume Augmentation with Autologous Costal Cartilage: A Case Report

This case report demonstrates that endoscopic reconstruction of the inferior meatus using autologous costal cartilage grafts is an effective therapeutic option for a patient with severe Empty Nose Syndrome, resulting in significant symptomatic improvement and graft stability at six months post-operation.

Original authors: Juan J. Vélez-Rodríguez¹, Guido J. Escobar-Barona¹, Andrés Carvajal-Rodríguez¹, Jorge Alirio Holguín-Ruíz¹, Valentina Fajardo-Astudillo

Published 2026-08-18
📖 4 min read☕ Coffee break read

Original authors: Juan J. Vélez-Rodríguez¹, Guido J. Escobar-Barona¹, Andrés Carvajal-Rodríguez¹, Jorge Alirio Holguín-Ruíz¹, Valentina Fajardo-Astudillo

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

The human nose is a marvel of biological engineering, designed not just to let air pass through, but to warm, humidify, and sense that air before it reaches the lungs. Inside the nasal cavity, there are bony structures covered in soft tissue called turbinates. These structures create turbulence, ensuring that the air we breathe interacts with the moist lining of the nose. When these turbinates are removed or severely reduced during surgery to treat chronic congestion, a strange and counterintuitive condition can arise. Patients find themselves unable to breathe comfortably despite having a wide-open airway. This paradox, where the nose feels blocked even though it is physically clear, is known as Empty Nose Syndrome. It is a distressing condition that often leaves patients feeling that their quality of life has collapsed, as the simple act of breathing becomes a source of anxiety and physical discomfort.

For years, the medical community has struggled to find a reliable way to fix this problem. The challenge lies in the fact that the missing tissue cannot simply be grown back. However, a new approach has emerged that focuses on rebuilding the space that was lost. A recent case report from Colombia details a successful attempt to restore the volume inside a patient's nose using a piece of her own cartilage. The story centers on a fifty-year-old woman who had undergone multiple nasal surgeries in the past, including the partial removal of her inferior turbinates. Over time, her condition worsened. She suffered from persistent blockage and a runny nose that did not respond to standard treatments like steroid sprays or saltwater rinses. Her daily life was significantly impaired, and she felt that her breathing was impossible to manage.

When doctors examined her, they found that the tissue on the lower side of her nasal passages had shrunk severely, leaving too much empty space. To confirm that her symptoms were indeed caused by this lack of volume, they performed a simple test. They placed a small piece of cotton inside her nose to temporarily fill the gap. The result was immediate and dramatic: her feeling of obstruction vanished, and her self-reported pain score dropped sharply. This test confirmed that the problem was not a blockage, but a lack of structure. The solution proposed was to permanently replace that missing volume. The surgical team decided to use a graft made from her own rib cartilage, a material known for being strong and compatible with the body.

The procedure involved carefully placing these cartilage pieces under the lining of the nose to rebuild the lower nasal passage. The surgeons created small pockets in the tissue and inserted the grafts to restore the shape and size of the area that had been lost. They also corrected a separate issue with her nasal valve, the narrowest part of the airway, to ensure the air could flow smoothly. The surgery was performed using an endoscope, a thin tube with a camera, allowing for a precise and minimally invasive approach. The goal was not just to fill the space, but to create a structure that would mimic the natural function of the missing turbinates, restoring the sensation of airflow.

Six months after the operation, the results were clear. A follow-up examination showed that the cartilage had integrated well with the surrounding tissue and had maintained its shape without shrinking away. More importantly, the patient's symptoms improved drastically. Her scores on standardized questionnaires, which measure the severity of empty nose syndrome and general nasal health, showed a massive reduction in distress. The score that measured her specific symptoms of empty nose syndrome dropped by half, and her overall sense of well-being returned to a level close to normal. She reported that her feeling of obstruction had lessened significantly, moving from a severe level to a mild one. The surgery did not cause any major complications, and the patient did not experience the rejection or failure that sometimes occurs with synthetic implants.

This case offers a promising glimpse into how surgeons might treat a condition that was once considered nearly impossible to fix. By using the patient's own tissue to rebuild the internal architecture of the nose, the team was able to reverse the paradoxical sensation of blockage. While this report focuses on a single patient and acknowledges that more research is needed to confirm these results across a larger group, it demonstrates that restoring the physical volume of the nasal cavity can lead to profound relief. The work suggests that for carefully selected patients who have suffered from the aftermath of excessive nasal surgery, reconstructive techniques using autologous cartilage may offer a viable path back to normal breathing and a better quality of life.

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