🧬 biology
TXNL1 Knockout Suppresses Pancreatic Cancer Cell Proliferation, Invasion, and EMT via Concomitant Inhibition of MEK/ERK and PI3K/AKT Signaling
This study demonstrates that TXNL1 is overexpressed in pancreatic ductal adenocarcinoma and drives malignant progression, including proliferation, invasion, and EMT, by activating the MEK/ERK and PI3K/AKT signaling pathways, thereby identifying it as a promising prognostic biomarker and therapeutic target.
Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of a preprint that has not been peer-reviewed. It is not medical advice. Do not make health decisions based on this content. Read full disclaimer
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