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The non-HDL cholesterol to HDL cholesterol ratio exhibits a ‘U’-shaped relationship with suicidal ideation in adolescents with depressive disorders: a cross-sectional study

This cross-sectional study of 291 adolescents with depressive disorders reveals a significant 'U'-shaped nonlinear relationship between the non-HDL to HDL cholesterol ratio and suicidal ideation, identifying a critical threshold of 2.63 where the risk is highest, thereby suggesting that both abnormally low and high lipid metabolism levels are associated with increased suicide risk in this population.

Original authors: Ting Wang, Ya-Qin Zhao, Ping Zhao, Jiao-Jiao Sun, Wen-Huan Xiao, Nan Liu, Jia Li

Published 2026-10-09
📖 1 min read☕ Coffee break read

Original authors: Ting Wang, Ya-Qin Zhao, Ping Zhao, Jiao-Jiao Sun, Wen-Huan Xiao, Nan Liu, Jia Li

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

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