Disruption of Mechanotransduction in Post-Infarct Cardiac Fibroblasts: A Computer Vision Protocol for the Identification of Cryptic Therapeutic Targets under Simulated Microgravity.

This paper proposes the Mechanobiological Vulnerability Index (MVI), a novel computational framework combining simulated microgravity and hybrid computer vision models to identify cryptic therapeutic targets in post-infarct cardiac fibroblasts by exploiting gravity-induced cytoskeletal vulnerabilities to overcome the limitations of static molecular profiling in treating cardiac fibrosis.

Original authors: João Victor Rocha da Silva