🧬 biology
SREBP2 regulates Gastric Cancer Progression and Immune Escape through TGF-β pathway–Mediated TAMs Polarization
This study demonstrates that SREBP2 drives gastric cancer progression and immune escape by promoting TGF-β-mediated M2 polarization of tumor-associated macrophages, which subsequently suppresses CD8⁺ T cell effector function.
Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of a preprint that has not been peer-reviewed. It is not medical advice. Do not make health decisions based on this content. Read full disclaimer
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