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Mechanistic study on PSMB9 and HLA-F regulating polyamine metabolism to mediate the malignant progression of glioma

This study identifies PSMB9 as a novel oncogene and prognostic biomarker in glioma that drives malignant progression and immune evasion by upregulating HLA-F, thereby modulating polyamine metabolism and offering a potential therapeutic target.

Original authors: Yan Cheng, Lin Zhang, Lina Zheng, Ting Wang, Weiwei Zhang

Published 2026-09-15
📖 1 min read☕ Coffee break read

Original authors: Yan Cheng, Lin Zhang, Lina Zheng, Ting Wang, Weiwei Zhang

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ⚕️ This is an AI-generated explanation of a preprint that has not been peer-reviewed. It is not medical advice. Do not make health decisions based on this content. Read full disclaimer

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