Auditory Epigenetic Transduction: Acoustic Perception Drives the c-Fos–SIRT6–SIRT3–Dicer Axis to Extend Health span

This study identifies a novel auditory epigenetic transduction mechanism wherein music listening activates a c-Fos–GATA2–SIRT6–SIRT3–Dicer axis to preserve microRNA processing and extend healthspan, a process quantitatively modeled as synergistically enhanced by aerobic exercise and dietary lycopene.

Original authors: Boominathan Lakshmanane