ASCC1 Promotes Malignant Progression of Pancreatic Cancer by Regulating the NF-κB Signaling Pathway

This study demonstrates that ASCC1 is overexpressed in pancreatic cancer, where it drives malignant progression and poor prognosis by activating the NF-κB signaling pathway to induce epithelial-mesenchymal transition and modulate the tumor immune microenvironment, highlighting its potential as a prognostic biomarker and therapeutic target.

Original authors: Nanzhang Wang, Rongwei feng, Heng Zhou, Chenghao Li, Jintao Cui, Fei Wang, Fucheng Wang, Yuqing Cui, Yong Chen