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The role of neoadjuvant systemic and regional chemotherapy in the treatment of gastric cancer: single tertiary level center experience of the last decade

This retrospective study of 343 gastric cancer patients over a decade demonstrates that neoadjuvant FLOT-based chemotherapy significantly improves five-year survival rates compared to other regimens, while the addition of HIPEC in selected advanced cases doubles median survival without increasing perioperative morbidity or mortality.

Original authors: Mindaugas Kiudelis, Žilvinas Dambrauskas, Danielė Bučinskaitė, Rita Gudaitytė, Agnė Šikarskė, Antanas Mickevičius, Almantas Maleckas, Audrus Ivanauskas

Published 2026-09-24
📖 1 min read☕ Coffee break read

Original authors: Mindaugas Kiudelis, Žilvinas Dambrauskas, Danielė Bučinskaitė, Rita Gudaitytė, Agnė Šikarskė, Antanas Mickevičius, Almantas Maleckas, Audrus Ivanauskas

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

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