13805 papers
This 24-year retrospective cohort study found that hyperbaric oxygen therapy was independently associated with significantly improved visual outcomes in patients with acute non-arteritic retinal artery occlusion, even among those presenting with worse baseline vision.
This national cross-sectional study of Kuwait's anti-doping program (2022–2023) reveals a 3.4% prevalence of adverse analytical findings among 667 athletes, with anabolic androgenic steroids being the most detected prohibited substances and no significant associations found between positive results and demographic or sport-related factors.
This five-year retrospective cohort study in Western Iran found that among 5,024 open-heart surgery patients, the 5.09% incidence of in-hospital cardiac arrest resulted in a low 16.5% survival rate to hospital discharge, with younger age, pre-existing coronary artery disease, and calcium gluconate administration identified as significant predictors of successful resuscitation.
This study demonstrates that a novel 3D-printed hydrogel encapsulating engineered exosomes derived from induced neural stem cells promotes sacral nerve regeneration by modulating macrophage polarization to alleviate inflammation.
This prospective study of 30 eyes demonstrates that gonioscopy-assisted transluminal trabeculotomy (GATT) is an effective and safe treatment for juvenile open-angle glaucoma, providing sustained intraocular pressure reduction and medication independence at 12 months regardless of baseline disease severity.
This study benchmarks machine learning models for cardiovascular disease classification across 46 countries using WHO STEPS data, revealing that complex algorithms offer only marginal performance gains over logistic regression while highlighting substantial geographic and temporal heterogeneity that necessitates prioritizing transportability, calibration, and minority-class performance over pooled ROC AUC in public health AI.
In a nationwide Chinese cohort, a higher burden of adverse childhood experiences was prospectively associated with an increased risk of developing symptomatic knee osteoarthritis, with frailty mediating a modest but statistically significant portion (17.4%) of this relationship.
This study demonstrates that the combined application of gingiva-derived mesenchymal stem cell conditioned medium and low-level laser therapy significantly enhances tongue wound healing in rats by accelerating re-epithelialization, promoting angiogenesis and muscle regeneration, and reducing inflammation more effectively than either treatment alone.
In a randomized non-inferiority trial of Chinese adolescents and young adults with bipolar depression, lurasidone demonstrated efficacy comparable to quetiapine over eight weeks but offered a distinct tolerability profile with lower sedation yet higher rates of akathisia and parkinsonism.
This two-center retrospective study of over 16,000 adults with type 2 diabetes and established atherosclerotic cardiovascular disease reveals that fewer than one-third received guideline-recommended cardioprotective therapies, with significant disparities driven by health system location, sex (specifically lower SGLT2 inhibitor use in women), and neighborhood socioeconomic disadvantage.