🧬 Category

q-bio

3881 papers

🧬 biology

Transcranial magnetic stimulation-based brain-computer interface with neurofeedback facilitates motor imagery of different daily life hand actions

This proof-of-concept study demonstrates that a novel, personalized transcranial magnetic stimulation (TMS)-based brain-computer interface combined with motor imagery and neurofeedback enables healthy adults to successfully modulate brain activity and decode complex, distinct hand actions, highlighting its potential for neurorehabilitation in individuals with severe motor impairments.

Hsiao-ju Cheng, Olivia Hochstrasser, Eunice Tai, Daryl Chong, Niccolò Voster, Chantal Wunderlin, Ingrid Angela Odermatt (…)2026-08-20
🧬 biology

S100A8/A9-TLR4 transcript, co-expression and proteomic query patterns in myocardial ischemia-reperfusion datasets and a CMR-defined microvascular obstruction thrombus resource: a descriptive secondary analysis

This descriptive secondary analysis systematically examines S100A8/A9-TLR4 transcript and co-expression patterns across public mouse myocardial ischemia-reperfusion datasets and a human CMR-defined microvascular obstruction thrombus proteomic resource, generating hypothesis-generating insights while explicitly noting the absence of established functional causality or clinical prediction.

Xiaofei Miao, Liping Shen, Weizhang Li, Haoran Chen, Yukun Xu, Lingyun Gu, Junyou Cui2026-08-20
🧬 biology

The circCRIM1–miR-320c–MMP16 Axis: A Regulator of Cartilage Differentiation and Homeostasis in Osteoarthritis with Therapeutic Potential

This study identifies the circCRIM1–miR-320c–MMP16 axis as a critical regulator of cartilage homeostasis in osteoarthritis, where upregulated circCRIM1 sponges miR-320c to derepress MMP16, impairing chondrogenesis and driving disease progression, thus highlighting its potential as a therapeutic target.

Yan Kang, Ming Li, Qiaojun Huang, Yiyi Jiang, Dianbo Long, Xijun Huang, Fangang Meng2026-08-20
🧬 biology

Proteostasis dysregulation is associated with astrocyte dysfunction and a KLF15–LRRTM4 regulatory axis in Alzheimer’s disease

This study integrates multi-cohort bulk and single-cell transcriptomic data to demonstrate that proteostasis dysregulation in Alzheimer's disease is consistently suppressed across cohorts, characterized by an interpretable diagnostic signature centered on KLF15, and driven by a specific KLF15–LRRTM4 regulatory axis within astrocytes.

Weihao Peng, Xiaojie Wu, Liang Sun2026-08-20
🧬 biology

LNCTAM34A promotes endometrial carcinoma progression through upregulation of C4orf47

This study reveals that the long non-coding RNA LNCTAM34A promotes endometrial carcinoma progression by upregulating C4orf47 through the suppression of miR-34a, a mechanism validated by single-cell transcriptomics and functional assays showing enhanced epithelial cell invasion and proliferation.

Bingfan Xie, Shangqiu Chen, Danhuan Lin, Zhengzhong Wu, Honghui Ou, Shuang Hou, Yong Chen, Feng Wang, Chunrong Qin, Lili (…)2026-08-20
🧬 biology

Subjective and Biological Indicators Capture Complementary Dimensions of Adaptation to Caregiving: Evidence from the Transition to Parenthood

This study demonstrates that the transition to parenthood reveals adaptation as a multidimensional process where subjective and biological indicators provide complementary, rather than interchangeable, insights, as evidenced by improved life satisfaction and biological health despite the absence of broad deterioration in other stress-related domains.

Chiara Costi, Pierluigi Sacco, Valentina Rotondi2026-08-20
🧬 biology

Isolation, Identification, and Pharmacological Screening of Leaf and Root Endophytic Bacteria from Avicennia officinalis in the Sundarbans, Bangladesh

This study isolates and identifies endophytic bacteria from *Avicennia officinalis* in the Sundarbans, Bangladesh, demonstrating that the selected *Staphylococcus haemolyticus* strain produces a crude extract with significant antibacterial and cytotoxic properties alongside moderate antioxidant activity, likely attributed to its alkaloid and phenol content.

Md. Alomgir Hossain, Sunzida Akter Eva, Sadia Sultana, Mohammad Nazir Hossain2026-08-20
🧬 biology

Gut Microbiota Dysbiosis Is Associated with Cardiometabolic Risks in Young Males Living in a Marine Environment: A Cross-Sectional Study

This cross-sectional study of 157 young males in a marine environment reveals that gut microbiota dysbiosis, influenced by specific dietary and lifestyle factors, is significantly associated with elevated cardiometabolic risks, including hyperlipidemia, hyperuricemia, and metabolic syndrome.

chunhong zhang, fengyuan wang, siyu xing, ziqi liu, dawei hu, di qin, tongyi sun, lin zhu, dong liang2026-08-20
🧬 biology

Molecular survey of Bartonella spp. and Ehrlichia canis from sampled ticks of small ruminants in Kurdistan province, Western Iran

A molecular survey of 519 ticks collected from small ruminants in Kurdistan Province, western Iran, revealed the low-level presence of *Ehrlichia canis* DNA in specific counties and tick species while detecting no *Bartonella* spp., highlighting the need for continued surveillance of tick-borne pathogens in the region.

Mojdeh Fehri, Safoura Moradkasani, Meysam Moravedji, Siyamak Kakehkhani, Mahsa Farhoodi Moghaddam, Maryam Rahravani, Min (…)2026-08-20