🧬 Category

q-bio

1432 papers

📄 other

Biases, blind spots and signals in public One Health genome data for carbapenemase-producing Enterobacterales

An analysis of nearly 140,000 public genomic records reveals that while carbapenemase-producing Enterobacterales data exhibits distinct source-specific patterns, the overwhelming dominance of clinical samples highlights a significant surveillance blind spot in environmental, animal, and food sectors, indicating that repository composition rather than true prevalence drives current visibility.

Georgios Miliotis2026-07-27
📄 other

Evolving genetic landscapes of Plasmodium falciparum Kelch-13 polymorphisms in Nigeria: A systematic review and meta-analysis

This systematic review and meta-analysis reveals that *Plasmodium falciparum* Kelch-13 polymorphisms in Nigeria are highly diverse and independently emerging rather than dominated by a single mutation, underscoring the urgent need for sustained genomic surveillance to prevent the spread of artemisinin resistance.

Aaron Onyebuchi Nwana, Emmanuel Afolabi Bakare, Isaac Segun Oyedeji, Happiness Oluwatosin Ismail2026-07-27
📄 other

PtoJAZ gene family analysis in Poplar 741 and insect resistance identification for PtoJAZ10

This study comprehensively characterizes the 39-member PtoJAZ gene family in *Populus tomentosa* 741 and demonstrates that the overexpression of the MeJA- and herbivory-responsive PtoJAZ10 enhances insect resistance in transgenic tobacco by modulating jasmonic acid/abscisic acid levels, antioxidant enzyme activities, lignin accumulation, and key defense-related signaling pathways.

Mengying Sun, Lijiao Gu, Lianxiang Long, Xinghao Chen, Shijie Wang, Chunyu Wang, Min Jiang, Jun Zhang, Minsheng Yang2026-07-27
📄 other

Three-Dimensional Mapping of Exploratory Priority in a Full-Sphere Workspace Using Immersive Virtual Reality

This study utilizes an immersive virtual reality paradigm to map the non-uniform three-dimensional spatial organization of exploratory priority in healthy adults, revealing distinct patterns of lower-space omissions, leftward asymmetry, and medial-to-lateral scoring gradients within a full-sphere workspace.

Tatsuya Yamamoto¹, Hirotomo Yonehara¹, Taiyo Fujimoto¹, Yusuke Shiina¹2026-07-27
📄 other

Isolation and antigenic characterization of calcareous corpuscle-associated proteins from Taenia solium cysticerci

This study establishes a reproducible two-phase methodology for isolating calcareous corpuscles from *Taenia solium* cysticerci and characterizes their associated proteins as a diverse, immunoreactive set of at least 23 distinct bands, providing a foundational framework for future diagnostic and immunological research in cysticercosis.

Andrea Rivera, Adriana Paredes, Miguel Marzal, Patricia Sáenz, Mirko Zimic, Robert H Gilman, Hector H García2026-07-27
📄 other

Long-term responses of butterfly communities to peatland restoration are predictable

Based on a 19-year study of 18 Finnish peatland sites, the research demonstrates that while peatland restoration consistently benefits specialist butterfly species, the magnitude of these community responses is predictable from short-term outcomes and landscape context, offering a valuable opportunity for early evaluation of restoration effectiveness.

Merja Elo, Jenni Niku, Norbertas Noreika, Otso Ovaskainen, Pekka Punttila, Anssi Vähätalo, Leo Vähätalo, Veera Saari, Ja (…)2026-07-27
📄 other

Intragenic deletions from whole genome sequencing of 1054 suicide deaths

This study utilizes whole genome sequencing of 1,054 suicide deaths and 1,230 controls to identify eleven rare intragenic deletions with significantly elevated frequencies in suicide cases, implicating genes involved in mental health, neuronal function, and metabolic processes as potential contributors to suicide risk.

Hilary Coon, Emily DiBlasi, Thomas Nicholas, Eric Monson, Elliott Ferris, Andrey Shabalin, Logan Yefimov, Brooks Keeshin (…)2026-07-27
📄 other

Hypoxia-Preconditioned DPSC-EVs Couple Angiogenesis and Odontogenesis to Drive Dentin–Pulp Complex Regeneration via a Distinct miRNA Cargo

This study demonstrates that hypoxic preconditioning enhances the regenerative potency of dental pulp stem cell-derived extracellular vesicles by enriching them with specific miRNAs (hsa-miR-423-5p and hsa-miR-193b-3p) that synergistically couple angiogenesis and odontogenesis to drive successful dentin–pulp complex regeneration.

Mengying Li, Jiabin Xu, Anqi Liu, Lei Qi, Menghao Yu, Yihao Fu, Kaili Lin, Changyong Yuan, penglai wang2026-07-27
📄 other

Single-cell viral capture identifies injury-remodeling programs and host-response candidates in RSV-infected airway organoids

By reanalyzing single-cell RNA sequencing data from RSV-infected airway organoids with viral transcript capture, this study distinguishes direct infection responses from bystander effects to identify specific injury-remodeling programs and prioritize host-response candidates, such as CD73 and the SYK inhibitor Fostamatinib, for future therapeutic screening.

Rongrong Liu, Ziyu Liu, Pengbo Wang, Yi Zhang, Shiyuan Hou, Chenyu Zhang, Weina Guan, Shuhan Wang, Xing Sun, Chenxi Zhao (…)2026-07-25