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Prevalence of malaria among pregnant women attending ANC at public health institutions in Damote-Gale district, Southern Ethiopia

A cross-sectional study conducted in Damot Gale district, Southern Ethiopia, from March to May 2024, revealed a 10.5% malaria prevalence among pregnant women attending antenatal care, identifying multigravida status and the lack of long-lasting insecticidal nets or indoor residual spraying as significant risk factors.

Original authors: Kussa, Y., Lema, S.

Published 2026-09-23
📖 4 min read☕ Coffee break read

Original authors: Kussa, Y., Lema, S.

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ⚕️ This is an AI-generated explanation of a preprint that has not been peer-reviewed. It is not medical advice. Do not make health decisions based on this content. Read full disclaimer

In many parts of the world, a mosquito bite is more than just an itchy nuisance; it can be a gateway to a serious illness called malaria. This disease is caused by tiny parasites that travel through the blood, and while anyone can catch it, the danger is particularly acute for women who are expecting a baby. During pregnancy, a woman's immune system naturally shifts to protect the growing fetus, a change that unfortunately makes her more vulnerable to these parasites. When malaria takes hold in a pregnant woman, it often hides without causing obvious fever or chills, yet it can still steal nutrients from the baby, leading to low birth weight, premature delivery, or even the loss of the pregnancy. Because of this silent threat, health workers in malaria-prone regions focus intensely on protecting mothers, using tools like insecticide-treated bed nets and spraying the inside of homes to kill mosquitoes. Understanding exactly how widespread the infection is, and which specific groups of women remain most at risk, is essential for saving lives.

In the Damot Gale district of southern Ethiopia, researchers recently set out to measure this risk among women visiting local health centers for prenatal care. The team, led by scientists from Wolaita and Hawassa universities, visited four health centers over a three-month period in 2024. They invited nearly four hundred pregnant women to participate, explaining the study and asking for their consent. For each woman who agreed, a trained technician gently pricked a finger to collect a tiny drop of blood. This sample was spread onto a glass slide, stained with a purple dye to make the parasites visible, and examined under a microscope. The researchers were looking for two specific things: whether malaria parasites were present at all, and if so, which type of parasite was causing the infection. Alongside the blood tests, the team asked the women questions about their daily lives, their education, their income, and whether they used protective measures like bed nets or had their homes sprayed with insecticide.

The results revealed that malaria remains a significant challenge in this region. Out of the 389 women tested, roughly one in ten was found to have a malaria infection in their blood. The vast majority of these cases were caused by Plasmodium falciparum, the most dangerous type of malaria parasite, while a smaller number of women had the less severe Plasmodium vivax species. The study also painted a clear picture of who was most vulnerable. Women who were pregnant for the first or second time were more likely to be infected than those who had been pregnant many times before. This pattern suggests that women who have had multiple pregnancies may have built up a stronger natural defense against the parasite over time, whereas first-time mothers are still learning to fight it off.

The data also highlighted the powerful role of prevention. Women who slept under long-lasting insecticidal nets were far less likely to have malaria than those who did not. Even more striking was the impact of indoor residual spraying, a method where the walls and ceilings of homes are coated with a chemical that kills mosquitoes. Women living in houses that had been sprayed recently had a dramatically lower chance of infection compared to those in unsprayed homes. While most of the women in the study knew that mosquitoes spread malaria and understood the value of bed nets, the study showed that knowledge alone was not enough; the actual use of these tools made the critical difference. The researchers concluded that while malaria control efforts have made progress, the disease is still a major public health problem in Damot Gale. To protect mothers and their babies, health officials need to ensure that bed nets are not just available but are being used correctly, and that seasonal spraying of homes continues to be a priority.

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