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Prevalence of Cardiovascular Risk Factors and Global Cardiovascular Risk Among Patients in General Practice: A Cross-Sectional Study

This cross-sectional study of 426 patients in a Slovak general practice reveals a high prevalence of cardiovascular risk factors, with 70% classified as having high or very high global cardiovascular risk according to the SCORE2 model, underscoring the critical need for regular monitoring and management of modifiable risk factors.

Original authors: Tatiana Wrba, Marek Kucera², Diana Vondrova¹, Jana Babjakova¹, Jana Jurkovicova¹, Lubica Argalasova¹

Published 2026-07-09
📖 5 min read🧠 Deep dive

Original authors: Tatiana Wrba, Marek Kucera², Diana Vondrova¹, Jana Babjakova¹, Jana Jurkovicova¹, Lubica Argalasova¹

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

Imagine your heart as a high-performance engine in a car that's been driving for decades. You want it to run smoothly until you're ready to retire, but the road is full of hidden potholes and speed traps. A team of researchers in Slovakia decided to pull over 426 drivers (people aged 40 to 69) at a local general practice "pit stop" to check their engines. They didn't just look at the dashboard; they popped the hood to see exactly what was clogging the fuel lines and wearing down the tires.

The Big Discovery: The "High-Risk" Dashboard
The most startling finding? When the researchers ran the numbers using a special calculator called SCORE2 (which predicts the chance of a heart crash in the next 10 years), they found that 70% of these drivers were already in the "High" or "Very High" risk zone. That's like finding that out of every 10 cars in the parking lot, 7 have a warning light blinking red.

The men were in even more trouble than the women. About 86.6% of the men were flagged as high or very high risk, compared to 57.8% of the women. The researchers suggest this gap might be because women have a natural "shield" (estrogen) that helps protect their engines before they hit menopause, but once that shield fades, the risk catches up.

The Culprits: What's Clogging the Engine?
The study found a messy garage full of bad habits and physical signs. Here is what they found in the 426 patients:

  • The "Middle" Problem: A huge chunk of the group was carrying extra weight around their bellies. 76% of everyone had a waist-to-height ratio (WHtR) above 0.5. Think of this as a "belt buckle test." If your belt is more than half your height, your engine is under extra strain. The researchers found that for every step up in this ratio, the risk of a heart event went up significantly.
  • The Sugar and Fat Mix: 42.7% of the group had high blood pressure (hypertension), and 8% had Type 2 diabetes.
  • The Cholesterol Cloud: The oil in the engines was too thick. 65.3% of the drivers had LDL cholesterol (the "bad" kind) above 3 mmol/L, and nearly 50% had non-HDL cholesterol levels that were too high.
  • The Smoking and Drinking: 26.1% of the group were current smokers. While most people only drank occasionally, 9.4% of the men were heavy drinkers (consuming more than 100 grams of alcohol a week).

The "Alcohol Myth" and the Real Danger
Here is a tricky part. At first glance, the data looked like a tiny bit of alcohol might be a "magic potion" that lowers risk. Some earlier studies have hinted at this, but this paper argues strongly against it. When the researchers dug deeper, they found that excessive alcohol consumption was actually a massive danger sign.

In fact, the study found that people who drank too much were 9.12 times more likely to be in the high-risk category than those who didn't. The "protective" effect of occasional drinking didn't hold up when they did the serious math. The authors are very clear: don't start drinking to save your heart. The evidence suggests that if you are already drinking, cutting back is the safer bet, and random studies don't support the idea that a glass of wine is a health supplement.

The "Obesity Paradox" and Other Mysteries
The researchers also noticed something interesting about weight. While being overweight (BMI over 25) and obese (BMI over 30) were common, the study found that simply having a high BMI wasn't the only thing driving the risk. Instead, where the fat was stored mattered more. The "belly fat" (measured by waist circumference) was a much stronger predictor of trouble than just the number on the scale.

They also looked at the "obesity paradox," a theory that sometimes being heavier helps people survive a stroke. However, in this study of healthy-ish people getting check-ups, the extra weight was clearly a problem, not a shield.

How Sure Are They?
The researchers are very confident about the big picture: 70% of these patients are at high risk, and factors like diabetes, belly fat, and heavy drinking are real, measurable dangers. They used real blood tests and blood pressure readings, not just guesses.

However, they are a bit more cautious about a few specific details. For instance, they couldn't prove that high cholesterol alone was the sole cause of the high risk in their specific group, partly because they didn't have enough data on who was taking cholesterol-lowering medicine. They also noted that the "protective" effect of light drinking might just be a fluke caused by other hidden factors, so they aren't betting on it.

The Takeaway
The main message is that the "pit stop" check-up is vital. Many of these drivers thought they were fine, but the SCORE2 calculator showed they were speeding toward a crash. The good news is that the engine isn't broken yet. The researchers emphasize that risk isn't a fixed number; it changes. If you stop smoking, lose a little belly fat, or cut back on the heavy drinking, you can turn that red warning light back to green. But you have to check the dashboard regularly, because the road conditions change every day.

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