← Latest papers
📄 medicine

Traditional Hamstring Tendon Autografts Versus Peroneal tendon Autografts in reconstruction of isolated Anterior Cruciate Ligament: A Randomized Controlled Trial

This randomized controlled trial demonstrates that the peroneus longus tendon is a reliable autograft alternative to the hamstring tendon for ACL reconstruction, offering comparable functional outcomes and knee stability while providing a larger graft diameter and potentially reduced donor-site morbidity.

Original authors: Hossam Hamed

Published 2026-07-29
📖 4 min read☕ Coffee break read

Original authors: Hossam Hamed

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

Imagine your knee is a high-performance suspension system on a race car, designed to handle sharp turns, sudden stops, and heavy bumps. The star player in this system is the Anterior Cruciate Ligament (ACL), a tough, rope-like band that acts as the main anchor, keeping the shinbone from sliding too far forward under the thigh bone. When this ligament snaps—often during a sudden twist in sports like soccer or basketball—the whole suspension goes haywire, leaving the knee wobbly and unstable. To fix it, surgeons perform a "reconstruction," which is essentially swapping out the broken rope for a new one.

For years, the go-to replacement has been the hamstring tendon, harvested from the patient's own leg. Think of this like taking a spare tire from the back of your car to fix a flat on the front; it works great, but now you're missing a spare tire, and the process of taking it out can leave the car a bit weaker or cause a sore spot where the tire used to be. Recently, scientists have been hunting for a "spare tire" that doesn't leave the car feeling less secure. They've been eyeing the peroneus longus tendon, a rope-like structure in the lower leg near the ankle. The big question is: Can this ankle tendon do the heavy lifting for the knee without causing new problems in the foot or ankle?

This study, a randomized controlled trial conducted by researchers at Cairo University, set out to answer that question by pitting the old favorite (hamstring) against the new challenger (peroneus longus). They gathered 42 patients with isolated ACL tears and randomly split them into two teams. One team got the traditional hamstring graft, while the other received the peroneus longus graft. The researchers then watched closely for a year, checking how well the knees stabilized, how the patients felt, and whether the "donor sites" (where the tendons were taken from) healed well.

The results were a surprising twist for the new challenger. The peroneus longus tendon turned out to be a thicker, sturdier rope right out of the gate. The average diameter of the peroneus graft was 9.9 ± 0.6 mm, significantly larger than the hamstring graft's 8.5 ± 0.5 mm. In the world of ligaments, a thicker rope is often seen as a bonus, potentially offering better resistance against stretching or snapping later on. Furthermore, harvesting the peroneus tendon was a much faster job, taking only about 7.4 minutes compared to the 14.9 minutes required for the hamstring.

When it came to the actual performance of the knee, both groups were champions. A year after surgery, patients in both groups reported massive improvements in their knee function and stability, with scores on the Lysholm and IKDC scales jumping significantly. The knees were stable, the pain was gone, and the patients were back to their normal lives. There was no statistical difference in how well the knees performed between the two groups; both grafts successfully restored the "race car" suspension.

However, the real story was in the side effects. The hamstring group paid a price for their graft: they experienced noticeable muscle shrinkage (hypotrophy) in their thighs, with a loss of about 10.0 ± 2.37 mm in circumference. In contrast, the peroneus group barely lost any muscle mass, with a drop of only 2.59 ± 0.73 mm. As for the ankle, where the peroneus tendon was taken, the patients had no trouble. Their ankle strength and range of motion remained perfect, and they scored an impressive 97.42 ± 1.7 on the AOFAS Hindfoot Score, indicating excellent foot function. The researchers noted that the peroneus brevis tendon, which stays behind, acts like a backup engine, taking over the work so the ankle doesn't feel the loss.

The study suggests that the peroneus longus tendon is a dependable, safe, and effective alternative for ACL reconstruction. It offers a thicker graft, a quicker harvest, and less muscle loss in the thigh, all while keeping the ankle happy. While the study is limited by its one-year follow-up and relatively small group size, the findings indicate that this "ankle rope" is more than just a backup plan; it's a strong contender that might just be the perfect spare tire for the next generation of knee repairs.

Drowning in papers in your field?

Get daily digests of the most novel papers matching your research keywords — with technical summaries, in your language.

Try Digest →