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Clinical Effect of Using a 3D-Printed Personalized Percutaneous Guide in Transverse Tibial Transport for Patients with Diabetic Foot versus Conventional Surgery

This retrospective comparative study demonstrates that 3D-printed patient-specific percutaneous guide-assisted transverse tibial transport offers superior clinical outcomes, including reduced surgical trauma, less blood loss, better pain control, faster functional recovery, and accelerated ulcer healing, compared to conventional surgery for patients with diabetic foot.

Original authors: Yadi Zhang, Jiayi Wu, Guifeng Luo, Bo Shang, Zekai Ma, Wenyi Yang, Han Yan, Huanwen Ding, Qingtao Li

Published 2026-09-25
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Original authors: Yadi Zhang, Jiayi Wu, Guifeng Luo, Bo Shang, Zekai Ma, Wenyi Yang, Han Yan, Huanwen Ding, Qingtao Li

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

For millions of people living with diabetes, a small cut on the foot can become a life-altering crisis. When the disease damages nerves and narrows blood vessels, the body loses its ability to feel injury or send fresh blood to heal a wound. These non-healing sores, known as diabetic foot ulcers, are a leading cause of amputation. Surgeons have long sought ways to restart the flow of blood to these dying tissues. One established method involves a procedure called transverse tibial transport. In this technique, a surgeon creates a window in the shinbone and slowly moves a segment of bone sideways. This mechanical stretching acts as a signal to the body, prompting it to grow new blood vessels and repair the damaged circulation in the foot. While effective, the traditional way of performing this surgery requires a large incision and relies heavily on the surgeon's eye to drill holes and position metal pins, which can lead to variable results and significant trauma to the leg.

A team of researchers in China recently explored whether modern digital tools could make this delicate procedure safer and more precise. They asked a straightforward question: could a custom-made, 3D-printed guide help surgeons perform this bone transport with less damage to the patient? To find out, they looked back at the records of sixteen patients who underwent this surgery for severe diabetic foot complications. Seven of these patients received the new treatment, where surgeons used a personalized plastic template printed from the patient's own scan data to guide their drills. The other nine patients received the standard, conventional surgery without these digital aids. The researchers compared the two groups to see if the high-tech approach offered real benefits in terms of blood loss, pain, and how quickly the foot ulcers healed.

The results showed that the patients who received the 3D-printed guide fared better in almost every measurable way. Because the guide fit perfectly against the shape of the patient's leg, the surgeons could make smaller cuts and drill with greater accuracy. The group using the guide had an average incision length of just over six centimeters, compared to nearly eight centimeters for the conventional group. They also lost less blood during the operation, with an average loss of about eighteen milliliters versus twenty-seven milliliters for the others. The surgery itself was faster for the guide group, taking roughly ninety-four minutes on average, while the conventional group took nearly one hundred and four minutes. Perhaps most importantly for the patients' recovery, those with the guide reported significantly less pain after the operation, with their pain scores dropping to near zero, while the other group still reported moderate discomfort.

The benefits extended beyond the operating room. The patients who used the 3D-printed guide regained their ability to care for themselves more quickly, with their daily living scores improving more sharply than those in the conventional group. Their foot ulcers also healed faster, closing at a rate of about two square centimeters per week, compared to roughly one and a half square centimeters for the other group. While both groups achieved a perfect record of saving the limbs from amputation, the path to recovery was smoother for the guide group. One patient in the guide group developed a minor skin issue at the incision site that healed within five weeks, while three patients in the conventional group faced similar complications that took longer to resolve. The study suggests that by combining computer design with 3D printing, surgeons can perform this complex bone transport with a level of precision that reduces trauma and accelerates healing, offering a promising new tool for saving feet that might otherwise be lost.

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