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Increase in Methadone Treatment Episodes With Co-occurring Mental Health Disorders between 2013 and 2023

Between 2013 and 2023, the number of US methadone treatment episodes involving co-occurring mental health disorders nearly tripled, shifting toward an older, predominantly male population with higher rates of stimulant use, homelessness, and Medicaid coverage, thereby necessitating expanded capacity for integrated care and housing support.

Original authors: Yinfei Kong, Kechen Zhao, Alanis Goncalves Leite, Daniel Howard

Published 2026-10-05
📖 5 min read🧠 Deep dive

Original authors: Yinfei Kong, Kechen Zhao, Alanis Goncalves Leite, Daniel Howard

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

In the United States, a specific kind of medical care has long served as a lifeline for people struggling with addiction to opioids, a class of drugs that includes heroin and powerful prescription painkillers. This treatment often involves methadone, a medication that helps calm the body's intense cravings and withdrawal symptoms, allowing individuals to stabilize their lives. However, addiction rarely exists in a vacuum. Many people who seek this help also live with mental health conditions, such as depression or anxiety, creating a complex situation where the mind and the body are both in distress. Over the last decade, the landscape of drug use in America has shifted dramatically. The crisis has evolved from being driven primarily by prescription pills and heroin to a more chaotic mix involving illicitly made fentanyl and stimulants like methamphetamine. This changing environment raises a critical question for doctors and policymakers: as the drugs people use change, do the people walking through the doors of treatment centers change too? Understanding who is seeking help, what they are struggling with, and how they are supported is essential for building a system that can actually save lives.

A team of researchers set out to answer this question by looking at the records of nearly 76,000 people who received publicly funded methadone treatment and also had a diagnosed mental health disorder. They compared two distinct moments in time: the year 2013 and the year 2023. By examining the data from these two years, they could see how the profile of a patient in this specific type of care had transformed over a decade. The study focused on episodes where a person entered treatment and eventually left, whether they completed the program, dropped out, or were discharged by the facility. The researchers were not looking at unique individuals, but rather at the total number of treatment journeys recorded, which allowed them to see the scale of the changes occurring across the country.

The numbers revealed a massive surge in demand. In 2013, there were just under 19,000 treatment episodes that fit the criteria. By 2023, that number had nearly tripled, rising to more than 56,000. This represents a 198 percent increase in the volume of people seeking this specific combination of care. Alongside this growth, the people themselves looked different. The average age of a client increased from roughly 36 years old to nearly 40. The group also became less likely to include women, with the proportion of female clients dropping from nearly half to just over two-fifths. These shifts suggest that the population relying on these services is aging and that the gender dynamics of addiction treatment are evolving.

The substances driving these treatment episodes also told a story of significant change. In 2013, more than half of the clients reported using injection drugs, a figure that fell to just over a third by 2023. However, the use of stimulants skyrocketed. The percentage of clients reporting methamphetamine use jumped from a small fraction to nearly 15 percent. Similarly, the use of cocaine or crack rose from about 30 percent to nearly 39 percent. Alcohol use also became more common among this group. While the use of opioids remained the primary reason for entering methadone treatment, the presence of these other powerful drugs meant that the clinical challenges facing doctors and counselors had become more complicated. Unlike opioids, for which methadone is a proven, effective treatment, there is no medication with similar success for stimulant addiction. This means that treating a patient who is struggling with both opioids and methamphetamines requires a different, more intensive approach.

The way these patients were supported and where they lived also shifted. In 2023, a much larger share of clients relied on Medicaid, a government health insurance program for low-income individuals, as their primary way to pay for treatment. This reflects broader changes in how healthcare is funded and accessed in the country. The type of care received also changed; fewer people were in short-term detoxification programs, and many more were placed in residential or rehabilitation settings where they could live while receiving care. Despite these changes, the rate at which people successfully completed their treatment plans improved, rising from 31 percent to 41.5 percent. Yet, a troubling trend emerged regarding stability: the number of people who were homeless when they arrived for treatment increased from about 13 percent to nearly 20 percent. This suggests that while medical treatment is available, the social safety net, particularly regarding housing, is struggling to keep pace with the growing needs of this population.

The researchers noted that their work has limits. The data comes from public facilities and does not capture every person in private treatment. The records also do not specify the exact mental health diagnoses or how severe they were. Because the study compared two points in time without tracking the same individuals year after year, it can show that changes happened, but it cannot prove exactly why they happened. It remains possible that policy changes, economic shifts, or new reporting methods influenced the results. However, the picture that emerges is clear and urgent. The people seeking methadone treatment for co-occurring mental health disorders are older, more likely to be using stimulants, more likely to be homeless, and more likely to be covered by public insurance than they were a decade ago.

This transformation in the patient profile carries important weight for the future of addiction care. The systems designed to help these individuals may need to expand their capacity to handle stimulant use, which requires different tools than opioid treatment. They may need to better integrate mental health care with addiction services and strengthen their connections to housing and social support. As the population of people seeking help continues to grow and change, the services they receive must evolve to meet them where they are, addressing not just the chemical dependency, but the complex web of mental health and social instability that often accompanies it.

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