← Latest papers
📄 medicine

Breast Reconstruction After Nipple-Sparing Mastectomy with Simultaneous Mastopexy in the Large and Ptotic Breast: One Step Transformation

This retrospective study demonstrates that a single-stage breast reconstruction using a wide-based adipodermal NAC flap with prepectoral implant placement and simultaneous mastopexy is a safe and feasible option for patients with large, ptotic breasts, yielding acceptable complication rates and significant nipple repositioning.

Original authors: Weaam S Magram, Osama A. Samargandi, Zaher T Fadel, Mawaddah Alrajraji, Nora Tarabulsi, Hattan Aljaaly, Basim Awan

Published 2026-10-21
📖 5 min read🧠 Deep dive

Original authors: Weaam S Magram, Osama A. Samargandi, Zaher T Fadel, Mawaddah Alrajraji, Nora Tarabulsi, Hattan Aljaaly, Basim Awan

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

For many women facing breast cancer, the decision to remove breast tissue is a profound and necessary step, but the emotional and physical toll of losing the breast's natural shape and the nipple itself can be devastating. In recent years, surgeons have developed a method called nipple-sparing mastectomy, which removes the breast tissue while carefully preserving the nipple and the surrounding dark circle of skin. This approach offers a significant psychological benefit, allowing women to retain a more natural appearance without the need for complex, multi-stage surgeries to rebuild the nipple later. However, this technique has traditionally been reserved for women with smaller, firmer breasts. For those with larger, heavier breasts that sag significantly, the procedure has been considered too risky. The concern is that the blood supply to the nipple, which must travel through the skin and tissue that is being lifted and reshaped, might be cut off, leading to tissue death and the loss of the very feature the surgery aims to save.

A team of surgeons at King Abdulaziz University in Jeddah, Saudi Arabia, set out to test whether this delicate balance could be achieved even in women with large, sagging breasts. They focused on a specific group of patients who had previously been told they were not candidates for a single-step reconstruction. The researchers wanted to see if they could remove the breast tissue, lift the remaining skin to a higher position, and insert a new implant all in one operation, without using the temporary tissue expanders or special mesh materials that are often required in these difficult cases. Their goal was to determine if a specific way of keeping the nipple attached to a wide base of skin and fat could keep it alive and healthy, even when the breast was reshaped significantly.

The study involved thirty-one women who had undergone this combined procedure between 2021 and 2026. These women had breasts that were large and heavy, with many requiring the removal of over 400 grams of tissue. The surgeons used a specific marking pattern on the skin, similar to a classic design used for breast lifts, to guide the incisions. The key to their technique was how they handled the nipple. Instead of cutting it free, they kept it attached to a broad, wide-based flap of skin and underlying fat. This flap was designed to draw blood from two main sources: vessels running up from the chest wall near the breastbone and vessels coming from the lower part of the rib cage. By keeping these connections intact, the surgeons hoped to ensure the nipple received enough blood to survive the reshaping process.

Once the breast tissue was removed through a small opening on the side of the breast, the surgeons placed a silicone implant directly under the skin but above the chest muscle. They then carefully lifted the nipple and the attached skin flap to a new, higher position, securing it in place. The remaining skin was trimmed and stitched together to create a natural, lifted breast shape. The team was careful to avoid excessive tension on the skin, which could strangle the blood vessels, and they monitored the nipple's color and temperature throughout the operation to ensure it remained healthy. They did not use any artificial mesh to support the implant, relying instead on the patient's own tissue and the precise placement of the implant.

The results of this approach were promising. Out of the fifty-one breasts treated, the vast majority healed well, with the nipple surviving completely. Only two breasts experienced a total loss of the nipple, and a few others had minor areas of partial tissue loss. The researchers noted that the failures were linked to specific issues: in one case, the implant chosen was too large, creating too much tension on the skin, and in another, a blue dye used to mark the area was injected in a way that may have constricted the blood vessels. These findings suggest that the technique is safe, provided the surgeons are meticulous about selecting the right implant size and avoiding certain practices that could harm the blood supply. The women in the study had their nipples moved an average of over eight centimeters upward, a significant change that was achieved in a single surgery.

This work suggests that women with large, sagging breasts do not necessarily have to settle for a less natural-looking reconstruction or undergo multiple surgeries to get the nipple back. By preserving a wide base of blood-supplying tissue and carefully managing the tension on the skin, surgeons can offer a one-step solution that restores both form and function. The study highlights that while the procedure is complex and requires precise planning, it is a viable option for a group of patients who were previously excluded from the benefits of nipple-sparing mastectomy. The success of the technique depends heavily on careful patient selection, avoiding smoking, and ensuring that the blood supply is protected at every step of the operation. For these women, the ability to keep their nipple and achieve a natural shape in a single operation represents a significant advancement in breast reconstruction care.

Drowning in papers in your field?

Get daily digests of the most novel papers matching your research keywords — with technical summaries, in your language.

Try Digest →