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Latent profiles of eating disorder symptoms among transgender, gender diverse, and cisgender people with lived experience of eating disorders: associations with neurodivergent traits and gender dysphoria

This study identifies four distinct eating disorder symptom profiles among transgender, gender diverse, and cisgender individuals, revealing that the profile characterized by avoidant eating without typical eating disorder cognitions is uniquely associated with gender dysphoria and neurodivergent traits, thereby highlighting the need for transdiagnostic approaches and dual diagnoses of ARFID and anorexia nervosa in these populations.

Original authors: Kai S. Thomas, Grace H. Williams, Max Keith, Hannah Blackbrook, Rox Bainbridge, Jamie Merry, LEADING Lived Experience Advisory Group, Marc O. Williams, Samuel J. R. A. Chawner, Josie Henley, Kate Coop
Published 2026-07-20
📖 5 min read🧠 Deep dive

Original authors: Kai S. Thomas, Grace H. Williams, Max Keith, Hannah Blackbrook, Rox Bainbridge, Jamie Merry, LEADING Lived Experience Advisory Group, Marc O. Williams, Samuel J. R. A. Chawner, Josie Henley, Kate Cooper, Catherine R. G. Jones

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

Imagine the human mind as a vast, bustling city. In this city, there are different neighborhoods where people live and interact. One neighborhood is Eating Disorders, a place where people struggle with how they relate to food, their bodies, and the thoughts that swirl around them. For a long time, scientists studying this neighborhood mostly looked at one specific type of resident: cisgender people (those whose gender matches the sex they were assigned at birth). They built the city maps based on what they saw there. But recently, researchers realized they were missing a huge chunk of the population: Transgender and Gender Diverse (TGD) people. These are folks whose gender identity doesn't match the sex they were assigned at birth.

Another part of this city is Neurodivergence, a neighborhood where people's brains work in unique, often brilliant, but sometimes challenging ways. Two famous residents here are Autism and ADHD. People with these traits might experience the world with intense sensory details or have brains that crave routine and struggle with focus. Scientists know that people from the Neurodivergence neighborhood often visit the Eating Disorder neighborhood more frequently than others, but they didn't quite know how these two neighborhoods overlapped, especially for TGD folks. They also wondered about Gender Dysphoria, which is the deep distress someone feels when their body doesn't match who they know they are inside. The big question was: Do TGD people with eating disorders look different from cisgender people? Do their brains and their gender struggles mix together to create unique patterns of eating struggles that old maps just can't see?

This paper is like a team of cartographers who decided to redraw the map of the Eating Disorder neighborhood using a new, high-tech tool called Latent Profile Analysis. Instead of just asking, "Do you have Anorexia?" or "Do you have Bulimia?", they asked hundreds of people to describe their daily habits and thoughts in detail. They looked at 487 people (303 of whom were TGD) who had lived experience with eating disorders. They wanted to see if these people naturally grouped into different "cliques" or profiles based on their symptoms, and then checked if being TGD or having neurodivergent traits made you more likely to belong to a specific clique.

The researchers found that the Eating Disorder neighborhood isn't just one big, messy block; it's actually made up of four distinct, vibrant communities, or profiles.

  1. The "Avoidant Eaters Without the Worries" (18.7%): These folks avoid certain foods, have low appetites, or are scared of eating because of the texture or taste, but they don't obsess over their weight or shape. It's like eating only because you have to, not because you're trying to change your body.
  2. The "Low-Key Group" (23.8%): These people have very few eating struggles. They don't worry much about food, weight, or shape, and they don't binge or restrict much. They might be in recovery or just having a lighter moment.
  3. The "Avoidant Eaters With the Worries" (28.1%): This group is a mix. They have the same food fears and low appetites as the first group, but they also have the heavy, traditional worries about weight and shape. It's like having two different struggles happening at once.
  4. The "Binge Eaters With the Worries" (29.4%): This is the group most people might recognize from movies. They struggle with binge eating and have intense worries about their weight and shape.

Here is where the story gets really interesting. The researchers discovered that which "clique" you belong to isn't random; it's deeply connected to your gender and your brain type.

The "Avoidant Eaters Without the Worries" group was the most unique. The study found that if you had high levels of gender dysphoria (distress about your body), autistic traits, or ADHD traits, you were much more likely to be in this group. It's as if the distress of not feeling at home in your own body, combined with a brain that processes the world differently, leads to avoiding food for reasons that have nothing to do with wanting to be thin. The paper suggests that for these people, avoiding food might be a way to cope with the overwhelming feelings of gender dysphoria or sensory overload, rather than a desire to lose weight.

Interestingly, the study also found a special "super-charged" connection. If you were autistic and had high gender dysphoria, you were even more likely to end up in the "Avoidant Eaters With the Worries" group. It's like a double whammy where the sensory and emotional intensity of being autistic mixes with the pain of gender dysphoria, creating a complex storm of eating struggles that includes both food fears and weight worries.

The paper also gently pushes back against some old ideas. For a long time, people thought ADHD mostly led to binge eating. But this study found that while ADHD traits were linked to the "Avoidant" groups, they didn't seem to make people more likely to be in the "Binge Eating" group. This suggests that the link between ADHD and eating disorders is more complicated than we thought.

The researchers are careful to say that while they found these strong patterns, they can't say for sure why they happen yet (since they took a snapshot in time, not a movie). However, the map they've drawn is a huge step forward. It tells doctors and helpers that if they see a TGD person or a neurodivergent person struggling with food, they shouldn't just look for "classic" weight-loss obsessions. They need to look for food fears, sensory issues, and the deep distress of gender dysphoria. The study suggests that these groups might need a "dual diagnosis" approach—treating both the eating disorder and the underlying gender or neurodivergent needs together, because for many, the food struggle is just one part of a much bigger, more complex story.

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