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Clinical and Non-clinical Drivers of Home Hospice Duration of Care in Cancer Patients

This retrospective cohort study of nearly 12,000 Israeli cancer patients reveals that both clinical factors, such as Karnofsky Performance Status and sex, and non-clinical system factors, including health-plan membership and geographic location, independently influence the duration of home hospice care.

Original authors: Boaz Hovav, Sharona Tsadok Rosenbluth, Shuli Brammli-Greenberg

Published 2026-08-31
📖 7 min read🧠 Deep dive

Original authors: Boaz Hovav, Sharona Tsadok Rosenbluth, Shuli Brammli-Greenberg

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

When a person is nearing the end of life due to a serious illness like cancer, the goal of medicine often shifts from trying to cure the disease to ensuring the patient's remaining time is as comfortable and meaningful as possible. This approach, known as palliative care, focuses on relieving pain and addressing emotional, social, and spiritual needs. While this care can be provided in hospitals, many families and patients prefer to receive it at home, where they are surrounded by familiar surroundings and loved ones. Home hospice services are widely recognized as a way to improve a patient's quality of life while also reducing the heavy financial burden of hospital stays. However, the effectiveness of this care depends heavily on timing. If a patient receives home hospice for only a few days before passing away, they may not have enough time to fully benefit from the support and symptom management the team offers. Conversely, if the care lasts for many months without a corresponding increase in benefit, it can strain resources without adding value. Experts generally consider a stay of three to four months to be the ideal window, but in reality, the length of time patients spend in these programs varies wildly, often falling far short of that optimal period.

Researchers wanted to understand why this variation exists. They set out to investigate the specific factors that determine how long cancer patients remain in home hospice care before they pass away. To do this, they looked at a massive collection of real-world records from Israel, covering nearly twelve thousand adult cancer patients who received care between 2014 and 2022. The team analyzed a wide range of details, including the patient's age, gender, the specific type of cancer they had, and their physical ability to perform daily tasks at the time they entered the program. They also examined non-medical factors, such as which health insurance plan the patient belonged to and where they lived geographically. By studying these thousands of cases together, the researchers hoped to uncover whether the length of care was driven primarily by the patient's medical condition or by the structure of the healthcare system itself.

The data revealed a stark reality about how long these patients stayed in care. The average length of time was sixty days, but this number was misleading because it was pulled upward by a small number of patients who stayed for very long periods. The typical patient, represented by the median, stayed for only twenty-seven days. This means that half of all patients received less than four weeks of home hospice care, a duration that is likely too short to provide the full benefits of the service. The researchers found that the length of stay was not random; it was strongly linked to specific characteristics of the patient and the system around them.

One of the most powerful predictors of how long a patient stayed was their physical condition when they first joined the program. The researchers used a standard measure called the Karnofsky Performance Status, which essentially rates how well a person can care for themselves and carry out normal activities. Patients who entered the program with a higher score, meaning they were still quite active and independent, tended to stay in care much longer. For every ten-point increase in this score, the median length of stay increased by nearly seven days. This suggests that patients who are referred to hospice earlier, while they still have some energy left, are able to utilize the services for a more extended and beneficial period. In contrast, patients who were already very frail or dependent when they were referred often passed away shortly after admission, leaving little time for the care team to make a difference.

The type of cancer a patient had also played a significant role. Those with cancers of the central nervous system or head and neck tumors generally stayed in care longer than average. On the other hand, patients with blood-related cancers or gastrointestinal cancers often had much shorter stays. This difference likely reflects how quickly these diseases progress. Some cancers decline rapidly and unpredictably in their final stages, making it difficult for doctors to know when to refer a patient to hospice before it is too late. Other cancers follow a slower, more predictable path, allowing for an earlier transition to home care. Interestingly, the patient's age did not turn out to be a major factor once the researchers accounted for their physical condition and cancer type. While older patients might seem like they would have shorter stays, the data showed that their age alone did not determine how long they received care.

Perhaps the most surprising finding was that non-medical factors had a clear and independent influence on the length of care. Even after adjusting for how sick the patients were and what kind of cancer they had, the health insurance plan they belonged to still mattered. Patients covered by one specific plan, Maccabi, stayed in care longer than those covered by other plans, such as Clalit or Leumit. Since the patients in these different groups had similar levels of illness when they started, this difference suggests that the way the healthcare system is organized—how referrals are handled, how administrative processes work, or how services are managed—directly impacts how long a patient receives care. Similarly, where a patient lived made a difference. Those living in the southern and northern parts of the country tended to have longer stays than those living in central regions or major cities like Tel Aviv and Jerusalem. This geographic variation hints that local medical practices, family support structures, or the availability of alternative hospital beds might influence when and how long people receive home hospice.

The study also looked at whether the length of care was changing over time. While the raw numbers showed that the average stay increased from about forty-seven days in 2014 to seventy days in 2022, the statistical analysis suggested this was not simply a result of a general trend toward earlier referrals over the years. Instead, the increase appeared to be driven by changes in the mix of patients and the specific characteristics of the healthcare system during that period. This means that simply waiting for time to pass will not automatically solve the problem of short stays; specific changes in how care is delivered are likely needed.

The researchers concluded that the duration of home hospice care is shaped by a complex mix of the patient's physical health, the nature of their disease, and the organizational structure of the healthcare system. While a patient's functional status is the strongest predictor of how long they will stay, the fact that insurance type and location still matter indicates that there are systemic barriers or variations in practice that affect access to care. These findings suggest that to ensure patients receive the full benefits of home hospice, medical professionals and policymakers must look beyond just the patient's medical needs. They must also examine how referrals are made, how different insurance plans operate, and how care is distributed across different regions. By understanding these drivers, it may be possible to create a system where patients are referred at the right time, allowing them to spend their final days with the support they need, for as long as it is truly beneficial.

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