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Effects of combined intraoral and extraoral low-level laser therapy on postoperative complications after impacted mandibular third molar extraction: A randomized clinical trial

This randomized clinical trial demonstrates that combined intraoral (660 nm) and extraoral (808 nm) low-level laser therapy significantly reduces postoperative pain and swelling following impacted mandibular third molar extraction, though it showed no significant effect on trismus or dry socket incidence.

Original authors: Hasan Momeni, Mehdi Abrishami, Hanie Chitsaz Zadeh, Ilia Abrishami

Published 2026-07-16
📖 6 min read🧠 Deep dive

Original authors: Hasan Momeni, Mehdi Abrishami, Hanie Chitsaz Zadeh, Ilia Abrishami

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

Imagine your mouth is a bustling construction site. Every day, tiny workers (cells) are busy repairing roads, laying bricks, and clearing debris. But sometimes, a big project is needed: removing a stubborn, buried rock (an impacted wisdom tooth) that's been causing trouble for years. When the demolition crew (the surgeon) finally pulls that rock out, the site is left in chaos. The ground is bruised, the air is hot with inflammation, and the workers are in pain. This is why, after wisdom tooth surgery, many people wake up with throbbing cheeks, swollen jaws, and a mouth that feels like it's been glued shut.

For decades, the standard way to calm this construction site down has been to hand out chemical fire extinguishers—painkillers and anti-inflammatory drugs. But these chemicals can sometimes have side effects, like making your stomach grumble or your head spin. So, scientists started asking: Is there a way to help the healing crew work faster and happier without using so many chemicals? Enter "Low-Level Laser Therapy" (LLLT). Think of this not as a sci-fi weapon that burns things, but as a gentle, invisible flashlight that shines a specific kind of light onto the injury. This light acts like a super-charged vitamin for the cells, whispering, "Hey, wake up! Let's fix this faster!" It's a non-invasive way to try and turn down the pain and swelling without the heavy baggage of pills.

The Big Experiment: A Split-Mouth Showdown

In this study, a team of researchers decided to put this "healing flashlight" to the test. They wanted to see if shining this light on a fresh wisdom tooth socket would actually make the recovery better than doing nothing at all. To make sure the results were fair, they used a clever trick called a "split-mouth" design. Imagine you have two identical twins, but instead of two people, it's one person with two sides to their mouth.

They recruited 20 patients who needed to have both of their lower wisdom teeth removed. Here's the magic part: For each patient, one side of their mouth got the special laser treatment, and the other side got a "fake" treatment (a sham). The fake treatment looked and sounded exactly the same, but the laser was turned off. The patients didn't know which side got the real light, and the person measuring the results didn't know either. This is like a blind taste test where neither the eater nor the judge knows which cookie has the secret ingredient.

The laser used was a bit of a two-wavelength team. On the inside of the mouth, they used a red light (660 nm) on four spots around the hole. On the outside of the face, they used an infrared light (808 nm) on two spots near the jaw muscle. They did this right after the surgery was finished.

What Did They Find? The Good News and the "Meh" News

The researchers checked in on the patients at three different times: one day after, three days after, and one week after the surgery. They measured three main things: How much it hurt (pain), how puffy the face was (swelling), and how wide the mouth could open (trismus). They also kept an eye out for a nasty complication called "dry socket," where the healing blood clot falls out and the bone gets exposed.

The Pain Relief:
The results were pretty clear on the pain front. The side that got the real laser treatment hurt significantly less than the fake side.

  • Day 1: The laser side had a pain score of 3.2, while the control side was at 4.1.
  • Day 3: The laser side dropped to 1.7, while the control side was still at 2.8.
  • Day 7: The laser side was almost pain-free at 0.4, compared to 1.4 on the control side.
    The numbers show that the laser side was consistently happier and less sore. It's as if the laser helped the "pain alarm" turn down its volume much faster.

The Swelling:
When it came to puffiness, the laser didn't win immediately. On day 1 and day 3, both sides were about equally swollen. However, by Day 7, the laser side had a slight edge. The swelling on the laser side was 14.29 (measured in a specific way), while the control side was still a bit puffier at 14.70. It wasn't a huge difference, but it was statistically significant, meaning the laser helped the face go back to normal a bit quicker in the long run.

The Jaw Opening (Trismus):
Here is where the laser didn't do much. Trismus is that feeling where your jaw feels stiff and you can't open your mouth wide. The study found that the laser side and the control side were almost identical in how well they could open their mouths on days 1, 3, and 7. The laser didn't seem to make the jaw muscles any more flexible than the fake treatment did.

The Dry Socket:
Finally, they checked for dry sockets. This is a rare but painful complication. In the laser group, 2 out of 20 people (10%) got a dry socket. In the control group, 4 out of 20 people (20%) got one. While the laser group had fewer cases, the difference wasn't big enough to say for sure that the laser prevented it. It's possible the laser helped, but with only 20 people, the study wasn't big enough to prove it with certainty.

The Verdict

So, what's the takeaway? This study suggests that using a combination of red and infrared lasers right after pulling a wisdom tooth is a safe and effective way to reduce pain for the first week and reduce swelling by the end of the first week. It's like giving the healing cells a little boost that makes the first few days much more comfortable.

However, the paper also rules out a few things. It suggests that this specific laser setup does not help with jaw stiffness (trismus) and does not definitely prevent dry sockets, at least not with the current method and sample size. The authors are careful to say that while the results are promising, they need more studies with bigger groups of people to be absolutely sure about the dry socket prevention and to figure out if different laser settings could help with the stiff jaw.

In short, if you're worried about the throbbing ache after wisdom tooth surgery, this "healing flashlight" might be a helpful tool to add to the toolbox, but it's not a magic wand that fixes every single problem.

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