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Factors Associated With an Increase in Substance-induced Psychosis Among Young Male Adults Aged 15-30 Years: A Qualitative Case Study at Ndola Teaching Hospital Psychiatric Unit, Zambia

This qualitative case study at Ndola Teaching Hospital identifies that the rising prevalence of substance-induced psychosis among young Zambian males (aged 15–30) is primarily driven by a combination of poor health knowledge, normalized substance use attitudes, and socio-economic vulnerabilities such as unemployment and poverty, necessitating targeted education and livelihood interventions.

Original authors: Kelvin Kemmus Mulenga, Thamary Karonga, Kudzai Thelma Munyoro

Published 2026-09-16
📖 5 min read🧠 Deep dive

Original authors: Kelvin Kemmus Mulenga, Thamary Karonga, Kudzai Thelma Munyoro

Original paper licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). ✨ This is an AI-generated explanation of the paper below. It is not written or endorsed by the authors. For technical accuracy, refer to the original paper. Read full disclaimer

In many parts of the world, the mind can become unmoored from reality when certain chemicals enter the body. This condition, known as substance-induced psychosis, is not a permanent change in the brain's wiring like schizophrenia, but rather a temporary state where a person experiences vivid hallucinations or holds firm beliefs that are not true, triggered directly by drugs or alcohol. It is a distinct medical event where the substance itself is the clear cause, and the symptoms usually fade once the chemical leaves the system, though the experience can be terrifying and dangerous. While this phenomenon is recognized globally, its specific drivers in different communities remain a mystery. In places where young people face economic hardship and limited opportunities, understanding why this condition is rising is critical for public health. It is not just about the drugs themselves, but about the lives of the people using them, the environment they live in, and what they believe about the risks they are taking.

Researchers at Ndola Teaching Hospital in Zambia set out to understand a sharp and worrying rise in these cases among young men. Between 2022 and 2023, the hospital's psychiatric unit admitted 535 young males between the ages of 15 and 30 who were suffering from substance-induced psychosis. This number represented a significant jump, signaling that something fundamental was changing in the Copperbelt region. To find out why, a team of researchers conducted a deep, personal investigation. They did not rely on statistics alone but sat down with twenty of these young men, all of whom had been admitted to the hospital and were now stable enough to talk. Through long, open conversations, the researchers listened to the stories of these men to uncover the knowledge, attitudes, and daily realities that led them to this point.

The first thing the researchers discovered was a profound gap in understanding. Despite the severity of their condition, most of the young men did not know that their hallucinations and delusions were caused by the substances they were using. Many believed that only cannabis could lead to such mental disturbances, while others thought alcohol was harmless in this regard. Some participants admitted they only learned the connection between their drug use and their psychosis after they were already inside the psychiatric unit. This lack of knowledge meant that many did not see themselves as being at risk until it was too late. They viewed their drug use as a way to stay awake for work, to sleep, or simply to have fun, without realizing that these actions could trigger a break from reality.

Beyond what they knew, the study revealed how these young men viewed their world and their choices. For many, using substances was normalized by their peers and their communities. It was seen as a common way to cope with the stress of unemployment, poverty, and the loss of parents. In neighborhoods where jobs were scarce and days were long with nothing to do, substances became a tool for relief and a way to pass the time. The pressure to fit in with friends was a powerful force; if everyone around them was using, it felt natural to join in. This social environment made it difficult to see the danger, as the immediate benefit of feeling better or fitting in outweighed the abstract fear of future consequences.

The circumstances that led these men to the hospital were often rooted in their daily struggles. Almost every participant described a history of using substances to manage difficult emotions or situations. Some started as young as 15, introduced to drugs by family members or friends, and quickly moved from occasional use to daily habits. The substances they used were often cheap and easily available, including cannabis, alcohol, and local mixtures like "jenkem" and "artane." The researchers found that the intensity of use was a major factor; many were consuming these substances multiple times a day, often mixing them together. This heavy, frequent use, starting at a young age when the brain is still developing, appeared to be a direct path to the severe psychotic episodes that landed them in the hospital.

The path to getting help was also fraught with obstacles. Many of the young men and their families delayed seeking medical treatment because of the stigma surrounding mental illness. In their communities, having a psychotic episode was often seen as a sign of weakness or a spiritual problem, leading families to hide the issue or turn to traditional healers first. By the time they reached the hospital, the situation had often escalated into a crisis. The researchers noted that the men themselves eventually recognized the need for professional help, but the journey to get there was slowed by shame and a lack of clear information about where to go.

The study concluded that the rise in substance-induced psychosis among young men in Ndola is not caused by a single factor, but by a combination of ignorance, economic hardship, and social pressure. The young men are not simply making bad choices in a vacuum; they are navigating a difficult environment where drugs are easy to find, jobs are hard to get, and the risks are not well understood. The researchers suggest that to turn the tide, efforts must go beyond just treating the symptoms in the hospital. They recommend that schools and community leaders provide clear education about the link between drugs and psychosis, while also creating opportunities for young people to work and engage in meaningful activities. By addressing the root causes of idleness and poverty, and by training community health workers to spot the early signs of trouble, the hope is that fewer young men will find themselves lost in a psychosis that could have been prevented.

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